Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation

doi:10.3748/wjg.v24.i1.5

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Jan 7, 2018 (publication date) through Oct 30, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 7, 2018; 24(1): 5-14
Published online Jan 7, 2018. doi: 10.3748/wjg.v24.i1.5

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Figure 1 Bacteria affect the differentiation of T-cell subsets and thus influence the occurrence of inflammation. Different types of bacteria have different effects on T cell differentiation. SFB has an effect on TH17. Clostridum clusters IV, XIVa, and XVIII and Hsp65-LL can influence the differentiation of Treg cells. B. fragilis might affect the ratio of Th1/Th2 via TLR2. SFB: Segmented filamentous bacteria; Hsp65-LL: Hsp65-producing Lactococcus lactis; B. fragilis: Bacteroides fragilis.

Citation: Shen ZH, Zhu CX, Quan YS, Yang ZY, Wu S, Luo WW, Tan B, Wang XY. Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation. World J Gastroenterol 2018; 24(1): 5-14
URL: https://www.wjgnet.com/1007-9327/full/v24/i1/5.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i1.5