Prediction of hepatocellular carcinoma development by aminotransferase to platelet ratio index in primary biliary cholangitis

Figure 1 Flowchart illustrating case search and identification process. HBV: Hepatitis B virus; PBC: Primary biliary cholangitis; UDCA: Ursodeoxycholic acid.

Figure 2 Cumulative hepatocellular carcinoma incidence. A: Whole cohort; B: Stratified by APRI-r1. APRI-r1: AST/platelet ratio index at 1-year.

Figure 3 Cumulative hepatocellular carcinoma incidence stratified by treatment response. A: Rotterdam criteria; B: Paris I criteria; C: Barcelona criteria; D: Toronto criteria.

Figure 4 Kaplan-Meier survival plot stratified by APRI-r1 and treatment response. A: Rotterdam criteria; B: Paris I criteria; C: Barcelona criteria; D: Toronto criteria. APRI-r1: AST/platelet ratio index at 1-year; low-risk (biochemical response with APRI-r1 ≤ 0.54), intermediate risk (suboptimal biochemical response with APRI-r1 ≤ 0.54, or biochemical response with APRI-r1 > 0.54) and high risk (suboptimal biochemical response with APRI-r1 > 0.54).