Oxidative stress, antioxidants and intestinal calcium absorption

doi:10.3748/wjg.v23.i16.2841

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2017; 23(16): 2841-2853
Published online Apr 28, 2017. doi: 10.3748/wjg.v23.i16.2841

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Figure 1 Schematic representation of the possible mechanisms involved in the inhibition of intestinal Ca²⁺ absorption caused by oxidative stress. TRPV6: Transient receptor potential vanilloid 6; TRPV5: Transient receptor potential vanilloid 5; IAP: Intestinal alkaline phosphatase; GSSG: Disulfide of glutathione; GSH: Glutathione; GPx: Glutathione peroxidase; GR: Glutathione reductase; SOD: Superoxide dismutase; CAT: Catalase; Cyt c: Cytochrome c; Cldns: Claudins; iNOS: Inducible nitric oxide synthase; NCX1: Intestinal Na⁺/Ca²⁺ exchanger; PMCA1b: Plasma membrane Ca²⁺- ATPase 1b; TJ: Tight junctions.

Citation: Diaz de Barboza G, Guizzardi S, Moine L, Tolosa de Talamoni N. Oxidative stress, antioxidants and intestinal calcium absorption. World J Gastroenterol 2017; 23(16): 2841-2853
URL: https://www.wjgnet.com/1007-9327/full/v23/i16/2841.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i16.2841