Hepatic encephalopathy: Ever closer to its big bang

Figure 1 Hyperammonemia consequences (Modified from Bosoi 2009).

Figure 2 Portal vein ligation rat SM. MET, × 15000, showing bands like Z with reinforced shortened and with ruptures. Vacuoles are enlarged and merged. Triad with pathological changes; mitochondrial damage, including loss of matrix density, loss of crests, swollen, fusion and breaking of the membrane in the cytosol and myofibrillogenesis. Collagen is seen in the upper right corner (unpublished data).