Pancreatic cancer early detection: Expanding higher-risk group with clinical and metabolomics parameters

Figure 1 Example of metabolomics based analysis, allowing segregation of pancreatic ductal adenocarcinoma from benign cases. Heat map illustration of discriminant capability of a metabolite set derived from gas chromatography and liquid chromatography/mass spectrometry plasma metabolomics dataset comparing pancreatic ductal adenocarcinoma patients (Red or group 1; n = 110) and benign pancreas (includes benign cysts, chronic pancreatitis, and normal pancreas) (Green or group 2; n = 90). Metabolites are plotted on x-axis, and the cases on the y-axis. Blue color indicates data points with a value smaller than the median of the respective metabolite and the red indicates higher values. This candidate set of metabolites enabled the segregation of the two groups.