Proton pump inhibitors therapy vs H2 receptor antagonists therapy for upper gastrointestinal bleeding after endoscopy: A meta-analysis

Figure 1 Flow chart of study selection. RCTs: Randomized controlled trials.

Figure 2 Forest plot and risk of bias summary from the Cochrane risk of bias tool comparing proton pump inhibitors therapy vs H₂ receptor antagonists therapy efficacy for the recurrent bleeding rate. PPI: Proton pump inhibitors; H₂R: H₂ receptor antagonists.

Figure 3 Forest plot comparing the efficacy of proton pump inhibitors therapy vs H₂ receptor antagonists therapy for the recurrent bleeding rate mortality. PPI: Proton pump inhibitors; H₂R: H₂ receptor antagonists.

Figure 4 Forest plot comparing the efficacy of proton pump inhibitors therapy vs H₂ receptor antagonists therapy for the required surgery rate. PPI: Proton pump inhibitors; H₂R: H₂ receptor antagonists.

Figure 5 Forest plot comparing the efficacy of proton pump inhibitors therapy vs H₂ receptor antagonists therapy for blood transfusion units. PPI: Proton pump inhibitors; H₂R: H₂ receptor antagonists.

Figure 6 Forest plot comparing the efficacy of proton pump inhibitors therapy vs H₂ receptor antagonists therapy for hospitalization time. PPI: Proton pump inhibitors; H₂R: H₂ receptor antagonists.

Figure 7 Funnel plot evaluating the publication bias for recurrent bleeding rate.