Novel immunological and nutritional-based prognostic index for gastric cancer

Figure 1 Overall survival according to prognostic nutritional index (A), neutrophil-lymphocyte ratio (B), and platelet-lymphocyte ratio (C). The prognosis of patients with prognostic nutritional index (PNI) ≥ 48.2, neutrophil-lymphocyte ratio (NLR) ≤ 1.83, or platelet-lymphocyte ratio (PLR) ≤ 140 was more favorable than that of patients with PNI < 48.2, NLR > 1.83, or PLR > 140 (P < 0.001 for all).

Figure 2 Overall survival of patients with different disease stages according to prognostic nutritional index (A-D). A high prognostic nutritional index (PNI) was significantly associated with a longer overall survival in patients with stage II or stage III disease (P = 0.019 and P < 0.001, respectively).

Figure 3 Comparison of the areas under the receiver operating characteristic curve for survival of gastric cancer patients based on prognostic nutritional index and Canton score at the end of follow-up (A), or after 12 mo (B), 36 mo (C), or 60 mo (D). The areas under the receiver operating characteristic curve at these four points were significantly greater for Canton score than for prognostic nutritional index (PNI) (P = 0.024, P = 0.022, P = 0.030 and P < 0.001, respectively).