Gastroenterology case report of mesalazine-induced cardiopulmonary hypersensitivity

Figure 1 Radiograph of the chest and computed tomography scan before and after mesalazine suspension. A: Chest radiograph showing an enlarged cardiac silhouette due to a cardiac effusion during mesalazine treatment; B: Computed tomography (CT) scan of the chest revealing cardiomegaly due to a large pericardial effusion (maximum width of 33.6 mm) during mesalazine therapy; C: Normal chest radiograph after mesalazine withdrawal; D: CT scan of the chest showing a complete resolution of the pericardial effusion after suspension of mesalazine.

Figure 2 Transbronchial biopsy of the left inferior pulmonary lobe. A: An eosinophilic infiltrate throughout the alveolar septa, alveolar spaces and capillaries (HE stain, × 40); B: An eosinophilic infiltrate in the interior of capillaries (HE stain, × 100).