I.31, a new combination of probiotics, improves irritable bowel syndrome-related quality of life

Figure 1 Patient flow through the study according to CONSORT guidelines[37]. Note the similar number of loss to follow-up in all treatment arms. IBSQoL: Irritable bowel syndrome-related quality of life; VSI: Visceral Sensitivity Index.

Figure 2 Irritable bowel syndrome related quality of life score improvement compared to baseline after 42 d of treatment. A: Global scores improved significantly more in both treatment groups than placebo (Kruskall-Wallis test); B: Among the different domains, the mental status showed a significant improvement when compared to placebo.

Figure 3 Irritable bowel syndrome-related quality of life score response to probiotic and placebo therapy. Good response was defined as score improvement ≥ 15 points; poor response as score improvement 10-15 points; and non-response as score improvement < 10 points. The number of responders (score increment > 10) was significantly larger in both groups of patients treated with probiotics than in those treated with placebo (χ² test). IBSQoL: Irritable bowel syndrome-related quality of life.