Colonic preparation before colonoscopy in constipated and non-constipated patients: A randomized study

Figure 1 Flow chart of the included patients. ¹Fixed angulations or colonic neoplasia. NaP: Sodium phosphate; PEG: Polyethylenglicol.

Figure 2 Efficacy and compliance of different preparations. A: Preparation quality score obtained with different preparations (no statistical difference between groups). Values are expressed as the percentage of patients. Prep 1, 90 mL of sodium phosphate (NaP); Prep 2, 45 mL of NaP followed by 20 mg of bisacodyl; Prep 3, 4 L of polyethylenglicol (PEG); Prep 4, 2 L of PEG followed by 20 mg of bisacodyl; B: Percentage of patients who had satisfactory and unsatisfactory colonic cleansing in the overall analysis and in the subgroup of constipated and non-constipated patients. Constipated patients obtained a higher rate of satisfactory colonic cleansing with prep 2, (45 mL of NaP followed by 20 mg of bisacodyl) when compared to preparation 3 (4 L of PEG) (prep 2 vs 3, ^aP = 0.03); C: Endoscopist appraisal on the necessity to repeat colonoscopy due to inadequate preparation in the overall analysis and in the subgroup of constipated and non-constipated patients. Non-constipated patients assigned to prep 4 (2 L of PEG followed by 20 mg of bisacodyl) needed to repeat colonoscopy due to inadequate preparation more often when compared to patients assigned to prep 1 (90 mL NaP) (prep 4 vs 1, ^cP < 0.05); D: Compliance to different preparations in the overall analysis and in the subgroup of constipated and non-constipated patients. Prep 2 (45 mL of NaP followed by 20 mg of bisacodyl) vs 1 (90 mL NaP), 3 (4 L of PEG) and 4 (2 L PEG followed by 20 mg of bisacodyl), ^eP < 0.05; prep 1 (90 mL NaP) vs 3 (4 L of PEG) and 4 (2 L of PEG followed by 20 mg of bisacodyl), ^gP < 0.05; prep 1 (90 mL NaP) and 2 (45 mL of NaP followed by 20 mg of bisacodyl) vs prep 3 (4 L of PEG), ⁱP < 0.05.