Risk modification of colorectal cancer susceptibility by interleukin-8 -251T>A polymorphism in Malaysians

Figure 1 Various interleukin-8 -251T>A genotype patterns in sporadic colorectal cancer patients observed after genotyping using allele-specific polymerase chain reaction. The genotype was considered as homozygous wild type [interleukin (IL)-8 -251TT] when only one band appeared at the T allele. When two bands appeared, each at the A allele and T allele, it was considered as heterozygous variant (IL-8 -251TA). The homozygous variant genotype was characterized by the appearance of only one band at the A allele. M: DNA ladder; 1: Homozygous wild type (IL-8 -251TT); 2: Heterozygous (IL-8 -251TA); 3 and 4: Homozygous variant (IL-8 -251AA).