Brief Article
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 21, 2012; 18(11): 1249-1256
Published online Mar 21, 2012. doi: 10.3748/wjg.v18.i11.1249
Figure 1
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Figure 1 Immunohistochemistry of chemokine ligand 7 in gastric cancer and adjacent normal tissues. Chemokine ligand 7 (CCL7) staining is higher in the cytoplasm of gastric cancer cells (A) than in the cytoplasm of adjacent normal cells (B); CCL7 staining is equal in the cytoplasm of gastric cancer cells (C) and in the cytoplasm of adjacent normal cells (D); CCL7 staining is lower in the cytoplasm of gastric cancer cells (E) than in the cytoplasm of adjacent normal cells (F). (magnification, × 400).
Figure 2
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Figure 2 Immunohistochemistry of chemokine ligand 8 in gastric cancer and adjacent normal tissues. Chemokine ligand 8 (CCL8) staining is higher in the cytoplasm of gastric cancer cells (A) than in the cytoplasm of adjacent normal cells (B); CCL8 staining is equal in the cytoplasm of gastric cancer cells (C) and in the cytoplasm of adjacent normal cells (D); CCL8 staining is lower in the cytoplasm of gastric cancer cells (E) than in the cytoplasm of adjacent normal cells (F). (magnification, × 400).
Figure 3
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Figure 3 Immunohistochemistry of chemokine ligand 21 in gastric cancer and adjacent normal tissues. Chemokine ligand 21 (CCL21) staining is higher in the cytoplasm of gastric cancer cells (A) than in the cytoplasm of adjacent normal cells (B); CCL21 staining is equal in the cytoplasm of gastric cancer cells (C) and in the cytoplasm of adjacent normal cells (D); CCL21 staining is lower in the cytoplasm of gastric cancer cells (E) than in the cytoplasm of adjacent normal cells (F). (magnification, × 400).
Figure 4
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Figure 4 Kaplan-Meier survival curves for disease-free survival of 194 patients with gastric cancer. A: Categorized by chemokine ligand 7 (CCL7) expression, survival was significantly worse for patients with higher CCL7 expression than those with equal or lower CCL7 expression (P = 0.002); B: Categorized by CCL8 expression, no significant difference was observed among the three groups (P = 0.269); C: Categorized by CCL21 expression, survival was significantly worse for patients with higher CCL21 expression than those with equal or lower CCL21 expression (P = 0.001).