Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease

doi:10.3748/wjg.v17.i9.1095

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Mar 7, 2011 (publication date) through Nov 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2011; 17(9): 1095-1108
Published online Mar 7, 2011. doi: 10.3748/wjg.v17.i9.1095

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Figure 1 Mechanism of glucocorticoid resistance in inflammatory diseases. GR: Glucocorticoid receptor; GC: Glucocorticoid; FKBP5: FK506-binding protein 5; GRE: Glucocorticoid responsive elements; hGRα: Human glucocorticoid receptor α; Hsp: Heat-shock protein; Hop: Hsp70/Hsp90 organization protein; IPO13: Importin 13; P-gp: P-glycoprotein; SWI/SNF complex: Switching/sucrose non-fermenting chromatin remodeling complex.

Citation: Iudicibus SD, Franca R, Martelossi S, Ventura A, Decorti G. Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease. World J Gastroenterol 2011; 17(9): 1095-1108
URL: https://www.wjgnet.com/1007-9327/full/v17/i9/1095.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i9.1095