Hepatitis B virus and hepatocellular carcinoma at the miRNA level

Figure 1 Clustering of miRNA expression change profiles in acute and chronic hepatitis B virus infection, as well as hepatocellular carcinoma (linkage type: Average; similarity measurement: Pearson correlation coefficient). The miRNA expression change profiles (miECPs) of the acute and chronic infections are distant from the majority of the hepatocellular carcinoma (HCC) miECPs, indicating that the alterations of miRNA expression during hepatitis B virus (HBV) infection are different from those of HCC. Despite this, they are statistically correlated (see the main text).