Splenic infarction associated with sorafenib use in a hepatocellular carcinoma patient

Figure 1 Contrast-enhanced abdominal computed tomography. A wedge-shaped hypodense lesion in the spleen is consistent with splenic infarction (arrow). Hepatic artery catheter is seen in hepatic artery as artifact.

Figure 2 Follow up abdominal computed tomography (1 mo). New hypodense lesion has developed in upper level of the spleen (arrow).

Figure 3 Contrast-enhanced computed tomography scan in arterial phase at the time of diagnosis of initial splenic infarction (A) and 2 mo later (B). A: When splenic infarction was diagnosed, an approximately 4 cm x 4 cm sized hepatocellular carcinoma (HCC) (arrow) was shown in S6; B: Two months later, the size of HCC was enlarged to 5 cm × 5 cm (arrow) and an intrahepatic metastatic nodule was also seen (arrowhead) beside main mass.