Heme oxygenase system in hepatic ischemia-reperfusion injury

doi:10.3748/wjg.v16.i48.6068

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Dec 28, 2010 (publication date) through Nov 7, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 28, 2010; 16(48): 6068-6078
Published online Dec 28, 2010. doi: 10.3748/wjg.v16.i48.6068

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Figure 1 Putative mechanisms of heme oxygenase-1 antioxidant effect. HO-1: Heme oxygenase-1; BVR: Biliverdin; OFR: Oxygen free radicals; NADPH: Nicotinamide adenine dinucleotide phosphate.

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Figure 2 Heme oxygenase-1-mediated suppression of the inflammatory response in hepatic ischemia-reperfusion injury. HMGB1: High Mobility Group Box-1; TLR: Toll-like receptor; DAMPs: Danger-associated molecular patterns; TNFα: Tumor necrosis factor α; IL: Interleukin; OFR: Oxygen free radicals.

Citation: Richards JA, Wigmore SJ, Devey LR. Heme oxygenase system in hepatic ischemia-reperfusion injury. World J Gastroenterol 2010; 16(48): 6068-6078
URL: https://www.wjgnet.com/1007-9327/full/v16/i48/6068.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i48.6068