Comparative study of therapeutic effects of PPI and H2RA on ulcers during continuous aspirin therapy

Figure 1 Gastroduodenal ulcer healing was endoscopically achieved in proton pump inhibitors and histamine 2 receptor antagonists group patients. A: Gastroduodenal ulcer healing was endoscopically achieved in 88.5% of proton pump inhibitors (PPI) group patients and in 84.6% of histamine 2 receptor antagonists (H2RA) group patients. There was no significant difference between the two groups; B: Gastroduodenal ulcer healing in patients with non-pangastritis was endoscopically achieved in 88.2% of PPI group and in 86.7% of H2RA group. There was no significant difference between the two groups. NS: Not significant.

Figure 2 Improvement of abdominal symptoms was evaluated using gastrointestinal symptom rating scale scores. The scores were not significantly reduced after treatment as compared with before treatment in both proton pump inhibitors (PPI) and histamine 2 receptor antagonists (H2RA) groups. ^aNS vs before. NS: Not significant.