Development of fatal acute liver failure in HIV-HBV coinfected patients

Figure 1 Liver biopsy, low power magnification (100 ×). A: Hematoxylin and eosin stain showing a low power view of two cirrhotic nodule surrounded by fibrosis. The edges of the nodules and the fibrous septi contain intense chronic inflammatory infiltrate; B: Trichrome stain delineating fibrous septa that surround liver nodules in blue color.

Figure 2 Liver biopsy, high power magnification (hematoxylin and eosin stain, 600 ×). A: Marked portal inflammatory infiltrate composed of plasma cells and a few eosinophils; B: High power view of a cirrhotic nodule composed of markedly swollen hepatocytes, some with granular eosinophilic cytoplasm and intense inflammatory infiltrate at the interface between parenchyma and fibrosis.