Expression of matrix metalloproteinases 2 and 9 in human gastric cancer and superficial gastritis

Figure 1 Relative mRNA expression of 18S ribosomal RNA (18SRNA), hypoxanthine ribosyltransferase-1 (HPRT-1), matrix metalloproteinases 2 (MMP2) and MMP9 in three different groups of gastric mucosa tissues. Error bars represent the mean ± SD. ^aP < 0.05 vs normal condition.

Figure 2 Validation of quantitative gelatin zymography (qGZ) of human mucosal biopsy homogenates. A: Representative zymogram of tested samples; B: Representative standard curve generated from human recombinant MMP-2 across linear range of 0.039-1.25 ng/mL, used to generate arbitrary units from densitometric data; C: Differential gelatinase activity of each of the six bands activity detected in normal (open circle), gastritis (open square) and gastric cancer (close square). Error bars represent the mean ± SD. ^aP < 0.05 vs normal condition.