Copyright
©2009 The WJG Press and Baishideng.
World J Gastroenterol. Mar 7, 2009; 15(9): 1072-1078
Published online Mar 7, 2009. doi: 10.3748/wjg.15.1072
Published online Mar 7, 2009. doi: 10.3748/wjg.15.1072
Figure 1 Down-regulation of MMP-2 mRNA expression detected by RT-PCR.
Lane 1: Blank control; Lane 2: pGPU6 (-); Lane 3: pGPU6-1; Lane 4: pGPU6-2; Lane 5: pGPU6-3; Lane 6 : pGPU6-4.
Figure 2 Down-regulation of MMP-2 protein expression detected by Western blot.
Lane 1: Blank control; Lane 2: pGPU6 (-); Lane 3: pGPU6-1; Lane 4: pGPU6-2; Lane 5: pGPU6-3; Lane 6: pGPU6-4.
Figure 3 Effects of MMP-2 siRNA on tumor cell proliferation.
Figure 4 Effects of MMP-2 siRNA on tumor cell apoptosis.
A: pGPU6-1; B: pGPU6-2; C: pGPU6-3; D: pGPU6-4; E: pGPU6 (-); F: Blank control.
Figure 5 Cell invasion observed by CV stained (× 200).
A: Blank control; B: pGPU6-1; C: pGPU6 (-); D: pGPU6-2; E: pGPU6-4; F: pGPU6-3.
-
Citation: Zhi YH, Song MM, Wang PL, Zhang T, Yin ZY. Suppression of matrix metalloproteinase-2
via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. World J Gastroenterol 2009; 15(9): 1072-1078 - URL: https://www.wjgnet.com/1007-9327/full/v15/i9/1072.htm
- DOI: https://dx.doi.org/10.3748/wjg.15.1072