Screening serum hepatocellular carcinoma-associated proteins by SELDI-based protein spectrum analysis

doi:10.3748/wjg.14.1257

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Feb 28, 2008 (publication date) through Nov 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2008; 14(8): 1257-1262
Published online Feb 28, 2008. doi: 10.3748/wjg.14.1257

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Figure 1 SELDI spectra of serum samples from patients with HCC with HBV/cirrhosis, cirrhosis and chronic hepatitis B. Arrows represent seven common leading differential proteins with low MW, including five common down-regulated proteins in HCC serum (m/z 2870, 3941, 2688, 3165, 5483) and two common up-regulated proteins (m/z 3588, 2017) in HCC and cirrhosis, using Ciphergen SELDI Software 3.1.1 with Biomarker Wizard and subtraction difference analysis. The intensity of each band in the gel view reflects the peak area in the original spectrum. HCC, HCC with HBV/cirrhosis; C, cirrhosis; HBV, hepatitis B virus.

Citation: Cui JF, Liu YK, Zhou HJ, Kang XN, Huang C, He YF, Tang ZY, Uemura T. Screening serum hepatocellular carcinoma-associated proteins by SELDI-based protein spectrum analysis. World J Gastroenterol 2008; 14(8): 1257-1262
URL: https://www.wjgnet.com/1007-9327/full/v14/i8/1257.htm
DOI: https://dx.doi.org/10.3748/wjg.14.1257