Primary multiple extragastrointestinal stromal tumors of the omentum with different mutations of c-kit gene

Figure 1 Histological and immunohistochemical findings of the tumors. A: Histology of the tumor. The tumor is composed of cellular spindle cells. Hematoxylin and eosin (× 200). B: KIT immunostaining of the tumor. KIT is diffusely and strongly positive in the tumor cells (× 200). C: CD34 immunostaining of the tumor. CD34 is diffusely and strongly positive in the tumor cells (× 200).

Figure 2 Computer analysis of a part of exon 11 of the c-kit gene in the larger tumor. Deletion of codons 552-558 is noted. Asterisks show the deletion.

Figure 3 Computer analysis of a part of exon 11 of the c-kit gene in the smaller tumor. A mutation at codon 559 (GTT→GAT) is recognized (arrow).