Endoscopic and histopathological evaluation of acute gastric injury in high-dose acetaminophen and nonsteroidal anti-inflammatory drug ingestion with suicidal intent

Figure 1 Images of lesions according to the posture after the ingestion. A: Patients in the supine position following ingestion of NSAID; B: Patients in the upright position following ingestion.

Figure 2 Distribution of the localization of endoscopic lesions in patients in the standing and supine positions following ingestion.

Figure 3 Correlation between age and LS.

Figure 4 HE stain images, × 100. A: Acetaminophen only (10 000 mg) patient with LS = 4 and BS = 2. Erosion within superficial epithelium, fibrin clots on superficial lamina propria, widespread congested vessel structures and marked edema; B: Acetaminophen only (6000 mg) patient with LS = 3 and BS = 2. Focal erosion within superficial epithelium, extravasated erythrocyte clusters and congested veins.