Clinical features and management of primary sclerosing cholangitis

Figure 1 Cholangiographic finding in PSC. Cholangiogram demonstrating multifocal strictures with intervening saccular dilatation of both intrahepatic and extrahepatic bile duct characteristic of PSC. (Photograph courtesy of Dr. Rahul Pannala).

Figure 2 Cholangiographic findings in PSC. Magnetic resonance cholangiography demonstrating findings of PSC.

Figure 3 Fibro-obliterative lesions in PSC. Image shows an expanded portal area without two distinct fibro-obliterative lesions (arrows) in end-stage primary sclerosing cholangitis. There is no intact bile duct present in this portal area, only cross-sections of portal vein and hepatic artery branches (H&E, original magnification, 100 ×). Inset: Higher magnification of the fibro-obliterative lesion (Masson trichrome, × 400). (Photograph courtesy of Dr. Schuyler Sanderson).