Transrectal EUS-guided FNA biopsy of a presacral chordoma-report of a case and review of the literature

Figure 1 Post processing sagittal reconstruction of non-contrast pelvic CT demonstrating a hypo attenuating spherical lesion anterior to the coccyx.

Figure 2 Endoscopic ultrasound with the Olympus GF-UM160 radial echoendoscope demonstrates a well circumscribed hyperechoic lesion, with some focal areas of heterogeneous echotexture, corresponding to the lesion described in Figure 1.

Figure 3 Tissue section of the aspirate sample shows sheets of vacuolated "physaliphorous" cells, classic of chordoma. These cells demonstrate immunorea-ctivity with pan-cytokeratin and epithelial membrane antigen stains.