Rational prescription of drugs within similar therapeutic or structural class for gastrointestinal disease treatment: Drug metabolism and its related interactions

Figure 1 Chemical structures of five PPIs.

Figure 2 Metabolic differences between four PPIs (OME: omeprazole; LAN: lansoprazole; RAB: rabeprazole; PAN: Pantoprazole). Arrow thickness represents relative contribution to metabolism.

Figure 3 Stereoselective metabolism of omprazole in human.

Figure 4 Chemical structures of six H₂-receptor antagonists.

Figure 5 Chemical structures of seven benzamide-type gastroprokinetic agents.

Figure 6 Chemical structures of eight setrons.

Figure 7 Chemical structures of nine fluoroquinolones.

Figure 8 Chemical structures of four azole antifungals.