Host and viral factors contributing to CD8+ T cell failure in hepatitis C virus infection

doi:10.3748/wjg.v13.i36.4839

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Sep 28, 2007 (publication date) through Nov 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2007; 13(36): 4839-4847
Published online Sep 28, 2007. doi: 10.3748/wjg.v13.i36.4839

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Figure 1 A: Virus-specific CD8+ T cell responses are strong, multi-specific, and sustained in acute resolving HCV infection; B: Virus-specific CD8+ T cell responses are weak and narrowly focused in chronic HCV infection.

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Figure 2 Possible Mechanisms of CD8+ T cell failure in persistent HCV infection.

Citation: Neumann-Haefelin C, Spangenberg HC, Blum HE, Thimme R. Host and viral factors contributing to CD8+ T cell failure in hepatitis C virus infection. World J Gastroenterol 2007; 13(36): 4839-4847
URL: https://www.wjgnet.com/1007-9327/full/v13/i36/4839.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i36.4839