Dedifferentiated liposarcoma arising from the sigmoid mesocolon: A case report

Figure 1 A: Gross picture showing a 25 cm dedifferentiated liposarcoma arising from the sigmoid mesocolon. Notice the bowel mucosa is unremarkable except for a small ulcer (arrow); B: The well-differentiated component showing numerous lipoblasts and fibrous septae. The dedifferentiated component resembles a malignant fibrous histiocytoma with pleomorphic nuclei and tumor giant cells (HE, x 400); C: The area showing an abrupt transition from the well-differentiated component to the dedifferentiated component (HE, x 40); D: The dedifferentiated component invading into the bowel wall. The arrow points to the overlying bowel mucosa (HE, x 40).