Liu-stain quick cytodiagnosis of ultrasound-guided fine needle aspiration in diagnosis of liver tumors

Figure 1 Needle aspiration under real-time ultrasound guidance. The needle (larger arrow) is advanced into the liver nodular lesion (small arrows) through the abdominal wall and liver parenchyma under the direct guidance of US.

Figure 2 Cytodiagnosis of hepatocellular carcinoma by quick Liu stain showing scattered distribution of malignant cells bearing atypical naked (A) and large nuclei (B) with scanty cytoplasm but without trabecular structure and sinusoids (A: 100 x, B: 400 x) and bile pigmentation (arrows) in cytoplasma (C) (400 x).

Figure 3 Cytodiagnosis of well-differentiated hepatocellular carcinoma by quick Liu stain showing cytological features of well-differentiated HCC with thicked trabecular structure (A) and polygonal tumor cells bearing centrally placed nuclei with a mild degree of pleomorphism and enlargement (B) (A: 100 x, B: 400 x) and cellular monomorphism and mildly increased nuclear/cytoplasmic ratio (C). Glandular structure was present, but the reticular pattern was not shown in Liu stain.

Figure 4