Dynamic changes and mechanism of intestinal endotoxemia in partially hepatectomized rats

Figure 1 Dynamic changes of serum ET (EU/L) levels. PH: partial hepatectomy; SO: sham-operation; ^aP < 0.05, ^bP < 0.01 compared with 0h group (NC: normal control ); ^cP < 0.05, ^dP < 0.01, PH vs SO at corresponding time points.

Figure 2 Dynamic changes of serum DAO (U/L) levels. PH: partial hepatectomy; SO: sham-operation; ^aP < 0.05, ^bP < 0.01 compared with 0 h group (NC: normal control); ^cP < 0.05, ^dP < 0.01, PH vs SO at corresponding time points.

Figure 3 Correlation between serum levels of ET and DAO in PH group.

Figure 4 HE staining for histological examination of terminal ileum lesions. A: Normal morphology of small intestinal in NC group; B: Abnormal morphology of small intestinal at 6 h in PH group (x 200).

Figure 5 Ultrastructural changes of terminal ileum the staining with La. A: No La particles and widen cells gap among the intestinal cells of NC group; B: Few La particles and slightly widen cells gap among the intestinal cells of SO group at 6 h; C: More La particles and widen cells gap among the intestinal cells of PH group at 6 h; D: Lots of La particles and apparently widen cells gap among the intestinal cells of PH group at 12 h; E: Decreasing La particle deposit and widen cells gap among the intestinal cells of PH group at 24 h; F: No La particle deposit was observed among the intestinal cells and the degree of widen cells gap of PH group decreased at 48 h (× 10000).

Figure 6 Immunohistochemical staining of LYZ-positive cells in rat liver. The different staining intensity LYZ positive cells were observed in the cytoplasm of NC, SO and PH groups, surrounding the central vein(CV) and portal triad(PT). A: LYZ positive cells in NC group; B: LYZ positive cells in SO group at 6 h; C: LYZ positive cells in PH group at 6 h ; D: LYZ positive cells in PH group at 12 h; E: LYZ positive cells in PH group at 24 h ; F: LYZ positive cells in PH group at 48 h (SABC, × 200).