Detection of hepatitis B virus genotypes using oligonucleotide chip among hepatitis B virus carriers in Eastern China

Figure 1 Layout of probes and fluorescence images of results. Probes layout on the oligonucleotide chip (A). Following hybridization of Cy5-labeled fragmented DNA, as described in Materials and Methods, the fluorescent signals of different HBV genotypes were detected as follows: Genotype B (C), genotype C (D), mixed genotype (E). Blank template amplified by PCR also was hybridized to the chip and the image of the result is shown in (B).