Insulin sensitizers in treatment of nonalcoholic fatty liver disease: Systematic review

Figure 1 Literature search and selection.

Figure 2 ¹In this study, metformin was compared with vitamin E. We have included only the metformin-treated group, with biopsies at baseline and at the end of the study. RCT: Randomized controlled trial; NR: Not reported, NS: Not significant; NA: Not applied; QUICKI: Quantitative insulin sensitivity check index; HOMA: Homeostatic model assessment; KITT: K index of insulin tolerance test.

Figure 3 ¹Only seven patients in the treatment group. Information about the control group is not available; ²This study reported anemia as an adverse effect, but numerical data are not available. NR: not reported; NA: not applied; HOMA: homeostatic model assessment.