Expressions of sonic hedgehog, patched, smoothened and Gli-1 in human intestinal stromal tumors and their correlation with prognosis

doi:10.3748/wjg.v12.i35.5687

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Sep 21, 2006 (publication date) through Nov 8, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical Research

World J Gastroenterol. Sep 21, 2006; 12(35): 5687-5691
Published online Sep 21, 2006. doi: 10.3748/wjg.v12.i35.5687

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Figure 1 Immunohistochemical staining of Hh signaling components. Alkaline phosphatase reaction products demonstrating Shh (A), Ptc (B), Smo (C) and Gli-1 (D) expression. Shh is expressed in the cytoplasm, Ptc and Smo are expressed in both the cytoplasm and cell membrane, and Gli-1 is expressed in both the cytoplasm and nucleus of GIST cells (x 200).

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Figure 2 Immunohistochemical staining of human intestinal leiomyomas. Alkaline phosphatase reaction products demonstrating Shh (A), Ptc (B), Smo (C) and Gli-1 (D) expression (x 200).

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Figure 3 Immunohistochemical staining of human intestinal schwannomas. Alkaline phosphatase reaction products demonstrating Shh (A), Ptc (B), Smo (C) and Gli-1 (D) expression (x 200).

Citation: Yoshizaki A, Nakayama T, Naito S, Wen CY, Sekine I. Expressions of sonic hedgehog, patched, smoothened and Gli-1 in human intestinal stromal tumors and their correlation with prognosis. World J Gastroenterol 2006; 12(35): 5687-5691
URL: https://www.wjgnet.com/1007-9327/full/v12/i35/5687.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i35.5687