Immune therapy including dendritic cell based therapy in chronic hepatitis B virus infection

Figure 1 DC/antigen interactions have been shown in 4 steps. Three of these steps are accomplished in vitro (step 1-3) when HBsAg-pulsed DCs are prepared.

Figure 2 Potent immune modulatory capacity of HBsAg-pulsed DCs in HBV transgenic mice. HBV transgenic mice expressed HBsAg in the sera but not anti-HBs. After two injections of HBsAg-pulsed DCs, these mice became negative for HBsAg in the sera.