Local regulator adrenomedullin contributes to the circulatory disturbance in cirrhotic rats

Figure 1 Changes of the mean arterial pressure and serum NOx levels by acute administration of exogenous adrenomedullin. A: Arterial pressure; ^aP < 0.05 vs vehicle; ^cP < 0.05 vs AM 0.3 nmol/(kg∙min); B: serum NOx levels. mean ± SE. r = -0.72, P < 0.05, n = 6.

Figure 2 Adrenomedullin concentrations in the aorta in the control and cirrhotic rats (A) and their relation with the mean arterial pressure (B). ▲: Control rats, ○: Cirrhotic rats without ascites, ●: Cirrhotic rats with ascites. mean ± SE. n = 10.