Advanced gastrointestinal stromal tumor patients with complete response after treatment with imatinib mesylate

Figure 1 (A) Abdominal CT showing a tumor located near the urinary bladder (arrow); (B) abdominal CT showing complete response without tumor at the same level as Figure 1A; (C) [18F] fluoro-2-deoxy-D-glucose positron-emission tomography (PET) scanning PET revealing no tumor with metabolic activity in the whole body; (D) Direct sequencing analysis of DNA from patient 1 showed deletion and insertion mutation at codons 563-572 in exon 11 (arrow).

Figure 2 (A) Abdominal CT showing a huge retroperitoneal tumor invading the pancreas (arrow); (B) abdominal CT showing complete response without tumor at the same level as Figure 2A; (C) PET showing no tumor with metabolic activity in the whole body; (D) direct sequencing analysis of DNA from patient 2 showed deletion and insertion mutation at codons 556-557 in exon 11 (arrow).

Figure 3 (A) Abdominal CT showing a tumor located near the ileum (arrow); (B) abdominal CT revealing complete response without tumor at the same level as Figure 3A; (C) PET showing no tumor with metabolic activity in the whole body; (D) direct sequencing analysis of DNA from patient 3 showed insertion AY at codons 502-503 in exon 9 (arrow).