Effects of killing Helicobacter pylori quadruple therapy on peptic ulcer: A randomized double-blind clinical trial

Figure 1 Histological maturation of regenerating mucosa in three groups. A: New triple therapy: incomplete epithelium, poorly developed glandular structure and moderate inflammatory cell infiltration (light microscope 3.3×10); B: Killing Hp quadruple therapy: well-formed epithelia, well-developed glandular structure and fewer inflammatory cells (light microscope 3.3×10); C: Placebo: some layers of newly generated cells over the scar, very poorly developed glandular structure and dense infiltration of inflammatory cells (light microscope 3.3×10).

Figure 2 Ultrastructural features of regenerating mucosa in three groups. A: New triple therapy: well-formed epithelia, but short and irregular microvilli, short sugar chains and thin sugar coat of microvilli (electronmicroscope ×15000); B: Killing Hp quadruple therapy: well-formed epithelia, long and regular microvilli, long sugar chains and thick sugar coat of microvilli (electronmicroscope ×25000); C: Placebo: shorter and fewer microvilli, shorter sugar chains and thinner sugar coat of microvilli (electromicroscope ×15000).