Unicentric Castleman’s disease of the pancreas with massive central calcification

Figure 1 A: Enhanced CT shows a well-circumscribed hypervascular mass of soft tissue density with focal calcification in the tail of pancreas; B: 7. 5 MHz endosonography shows a well-circumscribed hypoechogenic mass (2.8 x 4.9 cm) with focal hyperechogenicity and without signs of infiltration.

Figure 2 Endoscopic retrograde pancreatography (ERP) shows no malignant stricture of the pancreatic duct and a slight parenchymography in the tail of the pancreas.

Figure 3 A: Germinal centers with hyalinized venules originating from a hypervascular mantle zone surrounded by small lymphocytes in a concentric onionskin pattern (hematoxylin and eosin); B: Areas of heterotopic calcification of the central part of the tumor (left panel) and hyaline deposits (right panel) (hematoxylin and eosin).