Anti-hepatoma effect of arsenic trioxide on experimental liver cancer induced by 2-acetamidofluorene in rats

Figure 1 Gross changes of rat's liver after treatment. A: The control group (4 weeks after NS injection); B: the treatment group (4 weeks after medium-dose As₂O₃ injection).

Figure 2 Pathological changes after treatment. A: The control group (4 weeks after NS injection, ×20); B: the treatment group (4 weeks after medium-dose As₂O₃ injection, apoptotic cell observed).

Figure 3 Changes of cell cycle phases after treatment. A: The control group (4 weeks after NS injection); B: the treatment group (4 weeks after medium-dose As₂O₃ injection, obvious hypodiploid peak).

Figure 4 VEGF-positive signals after treatment. A: The control group (4 weeks after NS injection, ×20); B: the treatment group (4 weeks after medium-dose As₂O₃ injection, ×20).

Figure 5 Micro-vessels by FVIIIAg staining after treatment,×20. A: The control group (4 weeks after NS injection); B: the treatment group (4 weeks after medium-dose As₂O₃ injection).