Best method of detecting prior Helicobacter pylori infection

Figure 1 The nitrocellulose strips of Helico Blot 2. 1 representative of immunoblot results: lane 1, positive control; lane 2, negative control; lanes 3-7, serial serum samples of a patient showing positive results.

Figure 2 Fluctuating positive rates of various H pylori-specific antigens and Helico Blot 2. 1 in 25 H pylori-infected patients were charted at half- year intervals during a 4-year follow- up period. The CIM was unreliable, because it maintained high positive rates for at least 3 years after H pylori eradication. Thirty-five and thirty-seven kilounits antibodies of H pylori showed significant seroconversion changes at 1 year after bacterial cure. The seropositive rates of 116 ku (CagA) and Helico Blot 2.1 were nearly 100% during the 4-year follow-up period.