Comparative study on radiosensitivity of various tumor cells and human normal liver cells

Figure 1 G₂ phase prematurely condensed chromosome spreads. A: SMMC-7721 cells after exposed to the γ-rays of 0.5 Gy; B: L02 cells after exposed to the γ-rays of 8 Gy. Arrows show the chromatid breaks, arrowheads show the isochromatid breaks.

Figure 2 Cell survival curve after exposed to γ-rays. All of four cell lines have a linear quadratic survival curve, which were good agreement with classical model.

Figure 3 G₂ chromosome breaks at various absorbed dose. A: chromatid breaks; B: isochromatid breaks.

Figure 4 Correlation between chromatid breaks and absorbed dose at 0, 24, and 48 h after exposed to radiation.

Figure 5 Kinetic repair of chromosome breakages within 48 h after L02 cell line was exposed to γ-rays. The chromatid breaks plus 46 (number of normal human chromosomes) make this change remarkably.