Viral replication modulated by synthetic peptide derived from hepatitis B virus X protein

Figure 1 Alignment of amino acid sequences of HBx from six mammalian hepadnaviruses.

Figure 2 Quantitative detection of HBV DNA by real-time PCR. HBV DNA levels were significantly increased by 3.5 µM of CP (^aP = 0.005, ^bP = 0.038).

Figure 3 ELISA detection of HBsAg. Three and a half µM CP could significantly inhibit intracellular HBsAg expression (^bP < 0.001).

Figure 4 ELISA detection of HBeAg. The level of intracellular HBeAg was significantly increased by 3.5 µM CP (^bP < 0.001).

Figure 5 Flow cytometric analysis of Bax and p53 proteins.