Dynamic changes of capillarization and peri-sinusoid fibrosis in alcoholic liver diseases

Figure 1 Changes of hepatocytes after HE staining. A: normal HE, B: 4 d HE, C: 4 w HE.

Figure 2 Changes of hepatocytes after Masson staining. A: normal Masson, B: 4 w Masson, C: 11 w Masson

Figure 3 Changes of hepatocytes observed by electron microscopy. A: fatty vesicle in hepatocytes, B: activated HSC and fibril, C: sinusoidal endothelium and basement, D: endothelium,less fenestrae.

Figure 4 Changes of type I collagen after immunohistochemical staining. A: col-I Normal group, B: Col-I in 4 w group, C: Col-I in 9 w group.

Figure 5 Changes of type IV collagen after immunohistochemical staining. A: col-IV Normal group, B: Col-IV in 4 d group, C: Col-IV in 2 w group, D: Col-IV in 4 w group, E: Col-IV in 9 w group, F: Col-IV in 11 w group.

Figure 6 Changes of laminin after immunohistochemical staining. A: laminin Normal group, B: Laminin in 4 d group, C: Laminin in 4 w group, D: Laminin in 9 w group, E: Laminin in 11 w group.