Proteomics to display tissue repair opposing injury response to LPS-induced liver injury

Figure 1 Partial 2-D images of mouse liver proteins from (a₁, a₂) a control animal and animals treated with 4 mg/kg i. p LPS (b₁, b₂) 6 h, (c₁, c ₂) 24 h, (d₁, d₂) 30 h. The spots representing proteins whose levels changed following LPS treatment are shown. a1, b1, c1, d1 represent the relative same partial map after different LPS-treated onset. a2, b2, c2, d2 represent another relative same partial map.

Figure 2 Peptide mass fingerprint of MDPP (spot447). The spot was in-gel digested with trypsin. After desalted, the peptide mixture was analyzed by MALDI-TOF-MS. All MALDI mass spectra were internally calibrated using masses from two trypsin autolysis products (monoisotopic masses 2163.05 and 2273.15).