Frequencies of poor metabolizers of cytochrome P450 2C19 in esophagus cancer, stomach cancer, lung cancer and bladder cancer in Chinese population

Figure 1 Typical electrophoresis pattern in detection of CYP2C19*2. Goal fragment was 139 bp. Lanes 1 and 8: DNA ladder; Lanes 2, 4 and 6: wild-type primers; Lanes 3, 5 and 7: mutant primers; Sample 1: homozygous wild-type (lanes 2 and 3); Sample 2: heterozygote (lanes 4 and 5); Sample 3: homozygous mutant (lanes 6 and 7).

Figure 2 Typical electrophoresis pattern in detection of CYP2C19*3. Goal fragment was 253 bp. Lanes 1 and 6: DNA ladder; Lanes 2 and 4: mutant primers; Lanes 3 and 5: wild-type primers. Sample 1: heterozygote (lanes 2 and 3); Sample 2: homozygous wild-type (lanes 4 and 5); No homozygous mutant found in this study.