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World J Gastroenterol. Feb 21, 2013; 19(7): 1068-1078
Published online Feb 21, 2013. doi: 10.3748/wjg.v19.i7.1068
Published online Feb 21, 2013. doi: 10.3748/wjg.v19.i7.1068
Long interspersed nuclear element ORF-1 protein promotes proliferation and resistance to chemotherapy in hepatocellular carcinoma
Fan Feng, Yin-Ying Lu, Xu-Dong Gao, Zhong-Xian Xu, Xiu-Juan Chang, Hong Wang, Jian-Hui Qu, Zhen Zeng, Chun-Ping Wang, Yong-Ping Yang, Clinical Research Center of Hepatocarcinoma, 302 Military Hospital, Beijing 100039, China
Fan Feng, Institute of Toxicology and Pharmacology, Chinese Academy of Military Medical Sciences, Beijing 100850, China
Fan Zhang, Jun-Lan Yang, Yun-Feng Zhu, Tumor Center, PLA General Hospital, Beijing 100853, China
Chuan-Fu Zhang, Jia-Jun Cui, Institute of Disease Control and Prevention, Chinese Academy of Military Medical Sciences, Beijing 100071, China
Alex Meredith, Jia-Jun Cui, Department of Cancer and Cell Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States
Yu-Tao Yang, Beijing Institute for Neuroscience, Capital Medical University, Beijing 100069, China
Author contributions: Feng F, Lu YY and Zhang F contributed equally to this work; Lu YY, Zhang F, Gao XD, Xu ZX, Yang YT, Qu JH, Zeng Z and Chang XJ performed the majority of experiments; Zhang CF, Wang H, Yang JL, Wang CP and Zhu YF provided some reagents and analytical tools and were also involved in revising the manuscript; Feng F, Cui JJ and Yang YP designed the study; Feng F and Cui JJ wrote the manuscript; Meredith A refined the manuscript and the experiment.
Supported by The Key Scientific and Technological Research Foundation of the National Special Purpose Program, No. 2008ZX10002-018
Correspondence to: Yong-Ping Yang, Professor, Clinical Research Center of Hepatocarcinoma, 302 Military Hospital, No. 100, the 4th West Ring Road, Beijing 100039, China. yongpingyang@hotmail.com
Telephone: +86-10-63879193 Fax: +86-10-63879193
Received: July 20, 2012
Revised: December 4, 2012
Accepted: December 27, 2012
Published online: February 21, 2013
Processing time: 217 Days and 14.9 Hours
Revised: December 4, 2012
Accepted: December 27, 2012
Published online: February 21, 2013
Processing time: 217 Days and 14.9 Hours
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