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World J Gastroenterol. Oct 21, 2012; 18(39): 5635-5639
Published online Oct 21, 2012. doi: 10.3748/wjg.v18.i39.5635
Published online Oct 21, 2012. doi: 10.3748/wjg.v18.i39.5635
A de novo germline MLH1 mutation in a Lynch syndrome patient with discordant immunohistochemical and molecular biology test results
Fabrice Airaud, Sébastien Küry, Ingrid Maury, Stéphane Bezieau, CHU Nantes, Service de Génétique Médicale, 9 quai Moncousu, 44093 Nantes Cedex 1, France
Isabelle Valo, Institut de Cancérologie de l’Ouest, Service d’Anatomie et Cytologie Pathologique, 2 rue Moll, 49933 Angers Cedex 9, France
Dominique Bonneau, Olivier Ingster, CHU Angers, Service de Génétique Médicale, 4 rue Larrey, 49933 Angers, France
Author contributions: Airaud F, Küry S and Bezieau S designed research and wrote the paper; Valo I performed the anatomopathology research; Maury I performed the molecular biology research; and Bonneau D and Ingster O performed the clinical investigation.
Correspondence to: Fabrice Airaud, MSc, CHU Nantes, Service de Génétique Médicale, 9 quai Moncousu, 44093 Nantes Cedex 1, France. fabrice.airaud@chu-nantes.fr
Telephone: +33-240-084299 Fax: +33-240-084026
Received: April 4, 2012
Revised: June 14, 2012
Accepted: July 18, 2012
Published online: October 21, 2012
Revised: June 14, 2012
Accepted: July 18, 2012
Published online: October 21, 2012
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