Caspase-cleaved cytokeratin-18 and tumour regression in gastro-oesophageal adenocarcinomas treated with neoadjuvant chemotherapy

doi:10.3748/wjg.v18.i16.1915

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Apr 28, 2012 (publication date) through Dec 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2012; 18(16): 1915-1920
Published online Apr 28, 2012. doi: 10.3748/wjg.v18.i16.1915

Caspase-cleaved cytokeratin-18 and tumour regression in gastro-oesophageal adenocarcinomas treated with neoadjuvant chemotherapy

Khaleel R Fareed, Irshad N Soomro, Khalid Hameed, Arvind Arora, Dileep N Lobo, Simon L Parsons, Srinivasan Madhusudan

Khaleel R Fareed, Khalid Hameed, Arvind Arora, Srinivasan Madhusudan, Laboratory of Molecular Oncology, Academic Unit of Oncology, School of Molecular Medical Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham University Hospitals, Nottingham NG5 1PB, United Kingdom

Irshad N Soomro, Department of Pathology, Nottingham University Hospitals, Nottingham NG5 1PB, United Kingdom

Dileep N Lobo, Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre, NIHR Biomedical Research Unit, Nottingham University Hospitals, Nottingham NG7 2UH, United Kingdom

Simon L Parsons, Department of Surgery, Nottingham University Hospitals, Nottingham NG5 1PB, United Kingdom

Author contributions: Fareed KR and Madhusudan S initiated the study, participated in its design and coordination, carried out the study, performed the statistical analysis and drafted the manuscript; Soomro IN conducted the histopathological analyses; Lobo DN and Parson SL were involved in the initiation of the study and manuscript preparation; Hameed K and Arora A were involved in manuscript preparation and correction; all authors approved the final version of the manuscript.

Correspondence to: Dr. Srinivasan Madhusudan, FRCP, PhD, Laboratory of Molecular Oncology, Academic Unit of Oncology, School of Molecular Medical Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham University Hospitals, Nottingham NG5 1PB, United Kingdom. srinivasan.madhusudan@nottingham.ac.uk

Telephone: +44-115-8231850 Fax: +44-115-8231849

Received: August 4, 2011
Revised: January 13, 2012
Accepted: February 8, 2012
Published online: April 28, 2012

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