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World J Gastroenterol. Feb 14, 2011; 17(6): 809-816
Published online Feb 14, 2011. doi: 10.3748/wjg.v17.i6.809
Published online Feb 14, 2011. doi: 10.3748/wjg.v17.i6.809
Clinical significance of K-ras and BRAF mutations in Chinese colorectal cancer patients
Hong Shen, Ying Yuan, Han-Guang Hu, Xiao-Xian Ye, Mo-Dan Li, Department of Oncology, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China
Xian Zhong, Department of Internal Medicine, Bin Jiang Hospital, Hangzhou 310052, Zhejiang Province, China
Wei-Jia Fang, Department of Medical Oncology, First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310003, Zhejiang Province, China
Shu Zheng, Key Laboratory of Cancer Prevention and Intervention of Ministry of Education, Cancer Institute, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China
Author contributions: Shen H supervised the study, acquired and analyzed the data, and drafted the manuscript; Yuan Y co-supervised the field activities and designed the analysis strategy; Hu HG and Zhong X reviewed and edited the manuscript; Ye XX, Li MD and Fang WJ interpreted the data; Zheng S designed the study, co-supervised the field activities, and revised manuscript critically for important intellectual content.
Supported by The Department of Education of Zhejiang Province of China, grant No. Y200804314; the Zhejiang Provincial Natural Science Foundation, grant No. R2090353; the Department of Science and Technology of Zhejiang Province, grant No. 2008C33039; and the Chinese Ministry of Health, grant No. N20100148
Correspondence to: Shu Zheng, Professor, Key Laboratory of Cancer Prevention and Intervention of Ministry of Education, Cancer Institute, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Road, Hangzhou 310009, China. zhengshu@zju.edu.cn
Telephone: +86-571-87784501 Fax: +86-571-87214404
Received: November 25, 2010
Revised: January 4, 2011
Accepted: January 11, 2011
Published online: February 14, 2011
Revised: January 4, 2011
Accepted: January 11, 2011
Published online: February 14, 2011
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