Brief Article
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World J Gastroenterol. Nov 7, 2010; 16(41): 5211-5224
Published online Nov 7, 2010. doi: 10.3748/wjg.v16.i41.5211
Smad7 dependent expression signature highlights BMP2 and HK2 signaling in HSC transdifferentiation
Bernd Denecke, Lucia Wickert, Yan Liu, Loredana Ciuclan, Steven Dooley, Nadja M Meindl-Beinker
Bernd Denecke, Interdisciplinary Centre for Clinical Research (IZKF) Aachen, RWTH Aachen University, 52074 Aachen, Germany
Lucia Wickert, Institute of Clinical Chemistry and Pathobiochemistry of RWTH-University Hospital, 52074 Aachen, Germany
Yan Liu, Steven Dooley, Nadja M Meindl-Beinker, Molecular Hepatology, Alcohol Induced Diseases, Department of Medicine II, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany
Loredana Ciuclan, Department of Biology, Babes-Bolyai University, 400084 Cluj-Napoca, Romania
Author contributions: Denecke B, Wickert L and Liu Y performed the majority of the experiments and were involved in editing the manuscript and preparing the figures; Ciuclan L was directly involved in discussing the results and editing the manuscript; Dooley S was involved in designing the study and providing financial support for this work; Meindl-Beinker NM was involved in designing and coordinating the study and writing the manuscript.
Supported by Deutsche Forschungsgemeinschaft DO373/6-1 and SFB TRR77, BMBF (HepatoSys), European Research Advisory Board and the Schlieben-Lange-Programm of the Ministerium für Wissenschaft, Forschung und Kunst of Baden-Württemberg and the Europäische Sozialfond
Correspondence to: Dr. Nadja M Meindl-Beinker, Molecular Hepatology, Alcohol Induced Diseases, Department of Medicine II, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. nadja.meindl-beinker@medma.uni-heidelberg.de
Telephone: +49-621-3834983 Fax: +49-621-3831467
Received: April 14, 2010
Revised: May 11, 2010
Accepted: May 18, 2010
Published online: November 7, 2010
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